PATHOLOGICAL CLIMAX BY MEN
To the pathological variants of menopause for men take an early climax and climacteric syndrome. The symptoms of neuro-endocrine alteration accumulate on the displays of defeat of vessels atherosclerosis, which for men is formed on 7-10 years before, than for women.

Clinical picture
A hypertensive syndrome appears the unsteady increase of arterial blood pressure, typical transitory hypertension. Systolic pressure which brings an increase over of pulse pressure rises more considerable.

Cardial syndrome appears the attacks of cardial pains, unconnected with the physical loading, which are badly removed by coronarolitic preparations. Pains are removed on a background treatment by androgen.

Vasoasthenic syndrome is characterized the promoted fatigueability and muscular weakness. The attacks of muscular weakness appear suddenly, does not depend on the physical loading, are investigation of violation of regional circulation of blood.

Sexual and urinary dysfunction is related to the decline of tone of urinary bladder, violations of functioning of prostata: disturb indefinite dull pains in the area of urinary bladder and other dysuric phenomena. A libido is stored, but there can be violations of copulative cycle.

Diagnostics
And physiology, and pathological climax is accompanied the decline of formation of androgens in testicles. But a pathological variant is accompanied violation of metabolism of hormones: formation of active androgens (androsterone, dehydroepiandrosterone) goes down, the index of androsterone/dehydroepiandrosterone goes down.

A large value in pathogeny of pathological masculine climax has violation of balance of estrogens. At a physiology climax excretion of active estrogens (estrone, estradiole) goes down for men, prevails nonactive metabolite estriole. At a pathological climax for men a compensate decline of excretion of estriole is absent, active estrogen prevails (estradiole). Hypertensive and vasoasthenic syndromes are accompanied the expressed predominance of active estrogen, increase of relation of estradiole to estriole, diminishing of excretion of estriole.

Treatment
Therapy must be complex, to include psychotherapy, medical gymnastics, physical therapy treatment.

The purpose of hormonal therapy is creation of optimum hormonal background: androgens promote reactivity of spinal centres of erection, proceed in a libido, diminish expressed of vegetative violations. Treatment by androgens must not be continuous - development of atrophy of gonads is possible. Apply complex hormonal preparation of testobromlecitum, that consists methyltestosterone, bromuralum and lecithin. The course of treatment makes 6 weeks: 2 weeks on a 1 pill 3 times per a day under a language after a meal, 2 weeks - on a 1 pill 2 times per a day, 2 weeks - on a 1 pill 1 time per a day. Treatment can be picked up thread in 3-4 months.

Application of one андрогенів is possible. Methyltestosterone appoint on a chart: 1 week - on a 1 pill (5 mg) 2 times per a day sub lingua after a meal, 2 weeks - on a 1 pill 1 time per a day, 2 weeks - for 1/2 pills 2 times per a day. Sometimes appoint intramuscular injections 1% or to a 5% solution of testosterone propionates daily or in a day during 2-3 weeks. For the protracted therapy use the prolonged androgenic preparations - sustanon-250 or omnadrenum for 1 ml intramuscular 1 time per a month during 3-6 months.